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Diabetes-Screening in der betriebsmedizinischen Praxis
Erprobung eines standardisierten kohlehydrathaltigen Frühstücks („Test-Frühstück G77“) zur Erhöhung der Teilnehmer-Compliance

Background: The growing prevalence of type 2 diabetes mellitus poses a massive problem in the day-to-day work environment. Effective screening for diabetes is therefore an important part of the occupational medical screening programme. However, acceptance of the oral glucose tolerance test (OGTT) - the gold standard for diagnosing diabetes mellitus - is only limited. The aim of our study was to develop a cost-effective and attractive testing procedure (a test breakfast with a defined level of glucose) that can be well-standardized and is widely accepted in the workplace.

Methods: As part of the workplace health promotion programme, a test breakfast with 76.8 g of glucose equivalents and an OGTT were provided in a cross-over study of healthy volunteers. The acceptance of the test breakfast compared with OGTT was recorded in a questionnaire, and blood glucose and insulin levels were measured in a fasting state as well as after 60 and 120 minutes after the meal.

Results: A total of 65 volunteers took part in the study. All the volunteers considered diabetes to be a serious illness. Only 3.1 % were of the opinion that an OGTT could be well-integrated into the work environment as a screening test, and 90.8 % of respondents preferred a test breakfast to the OGTT. The fasting blood glucose levels were 96.9 mg/dl before the test breakfast and 94.8 mg/dl before the OGTT. Blood glucose levels rose to 118.8 mg/dl 60 minutes after the breakfast and to 115.5 mg/dl after the OGTT, and fell to 91.8 mg/dl and 96.8 mg/dl respectively after 120 minutes. Insulin secretion was also comparable at all three times in both tests.

Conclusion: Providing a standardized test breakfast was seen as a more attractive test option and, in our sample, produced values that were comparable with the OGTT in terms of the glucose and insulin response. A test breakfast is a suitable first screening measure to increase the acceptance of diabetes screening in occupational medical programmes and thus can improve the options for early detection of diabetes.